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This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. This cytokine is mainly secreted by macrophage and bind to its receptors, tnfrsf1a/tnfr1 and tnfrsf1b/tnfbr.

Ha sido ampliamente validada para su uso en diversas aplicaciones de investigación, como cultivos celulares, inmunoensayos y estudios in vivo. Tnf alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (tnf) superfamily The carrier free version does not contain bsa.

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This product is an active protein and may elicit a biological response in vivo, handle with caution. Cell number was quantitatively assessed by prestoblue® cell viability reagent. Macrophages mainly produce this protein, and it plays a key role in inflammation and the acute phase reaction.

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