Molecular lassos that herd pulverized micronuclear chromosomes chromosome segregation errors generate a diverse spectrum of simple and complex genomic rearrangements 由德克萨斯大学西南医学中心的研究人员领导的一项发表在《Cell》杂志上的研究,为我们理解癌症生物学中的关键机制问题带来了新的突破,也为避免癌症耐药性提供了可能的新策略。 Cancer cells frequently harbor complex genomes that are characterized by numerical and structural chromosomal abnormalities
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Our laboratory investigates the cellular and molecular mechanisms that shape the chaotic mutational landscape of cancer genomes.
他们的研究结果发表在《Cell》杂志上,解释了一些肿瘤中的染色体如何进行大规模重排,并可能导致避免癌症耐药性的新策略。
Ly returned to ut southwestern to establish his independent group in the department of pathology, and, in 2025, dr He holds secondary appointments in cell biology, pediatrics, and the harold c Simmons comprehensive cancer center at ut southwestern.